Mechanotransduction: Vinculin Provides Stability when Tension Rises
نویسندگان
چکیده
By beautiful imaging and state-of-the-art experiments, vinculin is established to be a central switch in mechanotransduction at integrin-based focal adhesions. Cycles of tension-regulated vinculin switching control focal adhesion dynamics and signaling to enable polarized cell migration and alignment.
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عنوان ژورنال:
- Current Biology
دوره 23 شماره
صفحات -
تاریخ انتشار 2013